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Common gastrointestinal side effects include: Nausea — the most frequently reported side effect, particularly during dose escalation Vomiting — often linked to nausea and typically dose-dependent Diarrhoea and constipation — both have been reported, reflecting altered gut motility Decreased appetite — a desired therapeutic effect, but one that requires monitoring to ensure adequate nutrition Severe or prolonged vomiting and diarrhoea can lead to dehydration and, in some cases, acute kidney injury (AKI)
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